Trials in Neuropathic Diabetic Foot Ulceration: Time for a paradigm shift?

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Trials in Neuropathic Diabetic Foot Ulceration

D iabetic foot ulceration is a serious and expensive complication with considerable morbidity that affects up to 15% of diabetic patients during their lifetime; moreover, 80% of amputations are preceded by foot ulcers (1). Despite these facts, Mason et al. (2) concluded in their systematic review of treatments for foot lesions that the evidence base for treatments is poor. Furthermore, they cri...

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Neuropathic Diabetic Foot Ulcers

From the Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine (A.J.M.B., L.V.), and the Departments of Dermatology and Cutaneous Surgery (R.S.K.), Epidemiology and Public Health (R.S.K.), and Psychology (L.V.), University of Miami School of Medicine, Miami; the Veterans Affairs Medical Center, Miami (R.S.K.); and the Department of Academic Medicine, Manchester Royal Infir...

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Diabetes mellitus is a disease of complications and Diabetic Foot Syndrome is an important problem confronting society and health professionals. In USA one in four diabetics sustains foot ulcer and 40% of them lose their feet [1]. It accounts for 70% of non-traumatic amputations. In Joslin Diabetes Clinic, 25% admissions are due to foot ulcers. In Indian scene, the data is limited. In the study...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2003

ISSN: 0149-5992,1935-5548

DOI: 10.2337/diacare.26.9.2689